When trying to determine your best course of treatment and your prognosis, your doctor will take into account your phase of leukemia, as well as other factors. A prognosis is a statement about the prospect of surviving and recovering from a disease.
Factors that worsen your prognosis are called adverse prognostic factors. Those that improve your prognosis are called favorable prognostic factors. Your doctor looks at your prognostic factors as well your phase to help find the best treatment plan for you.
Here's a list of adverse prognostic factors.
You are in an accelerated phase or blast phase
You have an enlarged spleen.
You have increased numbers of basophils and eosinophils (types of granulocytes) in circulating blood samples.
You have very high or very low platelet counts.
You are age 60 or older.
Tests show you have multiple chromosomal changes in your CML cells.